If you are coming from I-44 and Highway 141, take Highway 141 towards Fenton. Then turn right onto Gravois. Go west on Gravios and get into the left lane so that you can turn left at the stoplight at Northwest Blvd. Be ready to make a very quick right onto Biltmore and look for Hope Animal Hospital at the top of the bluff -- under the big "Hope Animal Hospital" billboard and next door to Chuck's Boots.